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First-Order Elimination Kinetics
For most drugs, the amount of drug eliminated from the body during any time interval is proportional to the total amount of drug present in the body. In pharmacokinetic terms, this is called first-order elimination and is described by the equation Separa...
Leibniz's Notation
Who is Leibniz Gottfried Wilhelm Leibniz (1646 - 1716) was a 17th century German mathematician. He’s often credited with developing many of the main principles of differential and integral calculus, and is primarily recognized for what we now call Leibniz’s no...
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IoC C Colin WANG, Ph.D School of Mathematical Sciences, University of Lancaster Institution of Oncology, Chinese Academcy of Medical Science Data Science, Luye Pharma F ...
Modified Fibonacci Sequence
Fibonacci Sequence The classic Fibonacci sequence is defined by the linear recurrence equation: Which goes like 1, 1, 2, 3, 5, 8, 13, 21, 34, 55, 89, ... In another words, the next number in the sequence is equal to the sum of its two predecessors. The r...
A Review of Clinical Pharmacology Considerations in Antibody-drug Conjugates Approved by the US Food and Drug Administration Between 2000 and 2025
by Seoyoung Koo, Chae Yeon Kim, Jeong-hyeon Lim, Eunyoung Lee, In Young Kim, Young G. Shin, and Hanlim Moon Abstract Antibody-drug conjugates (ADCs) represent a promising class of anticancer therapies with rapidly expanding development. However, regulatory app...
Contributors List
IoC E Eric ZHANG, Ph.D, MBA School of Mathematics, Tsinghua University Data Science, Livzon Pharma J Junxian Zhao Clinical Development, Luye Pharma ...