# Math in Biometrics

# Mathematical Analysis

# Leibniz's Notation

<h3>Who is Leibniz</h3>
<p>Gottfried Wilhelm Leibniz (1646 - 1716) was a 17th century German mathematician. He’s often credited with developing many of the main principles of differential and integral calculus, and is primarily recognized for what we now call Leibniz’s notation.</p>
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  <img src="https://macrolib.com/uploads/images/gallery/2025-11/leibniz600.png">
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<h3>Leibniz's Notation System</h3>
<p>The derivative of a function based on today’s standard  is given by:</p>
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  <img src="https://latex.codecogs.com/svg.image?\displaystyle\lim_{\Delta&space;x\to&space;0}\frac{\Delta&space;y}{\Delta&space;x}=\displaystyle\lim_{\Delta&space;x\to&space;0}\frac{f(x&plus;\Delta&space;x)-f(x)}{\Delta&space;x}">
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<p>Leibniz's notation expresses the derivative as:</p>
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  <img src="https://latex.codecogs.com/svg.image?\frac{dy}{dx}=\frac{f(x&plus;dx)-f(x)}{dx}">
</div>
<p>where goes <img src="https://latex.codecogs.com/svg.image?dx" style="vertical-align:middle"> toward 0.</p>

<h3>Fractional Behavior</h3>
<p>Let’s review some examples where Leibniz’s notation is often utilized. The Chain Rule using Lagrange Notation states:</p>
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  <img src="https://latex.codecogs.com/svg.image?h^{'}(x)=f^{'}(g(x))g^{'}(x)">
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<p>We can translate the above Chain Rule into Leibniz's Notation as:</p>
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  <img src="https://latex.codecogs.com/svg.image?\frac{dy}{dx}=\frac{dy}{du}\frac{du}{dx}">
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<p>In the above equations, we can see how Leibniz’s Notation behaves similarly to a fraction, although it must be emphasized that the derivative is not a fraction.</p>

<h3>Try It on a Function</h3>
<p>Let us try <img src="https://latex.codecogs.com/svg.image?\inline&space;f(x)=x^{2}" style="vertical-align:middle">.</p>
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<summary>Click to Expand/Collapse</summary>
  <p>Expand the function:</p>
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    <img src="https://latex.codecogs.com/svg.image?\frac{dy}{dx}=\frac{(x&plus;dx)^{2}-x^{2}}{dx}=\frac{x^{2}&plus;2x(dx)&plus;(dx)^{2}-x^{2}}{dx}">
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  <p>Simplify fraction:</p>
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    <img src="https://latex.codecogs.com/svg.image?\frac{dy}{dx}=\frac{2x(dx)&plus;(dx)^{2}}{dx}=2x&plus;dx=2x">
  </div>
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</details>
<p>So the derivative of <img src="https://latex.codecogs.com/svg.image?\inline&space;&space;x^{2}"> is <img src="https://latex.codecogs.com/svg.image?\inline&space;&space;2x">.</p>